Ki20227

SKU: orb181032

Description

Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor with IC50 value of 2 nM; 6 fold and > 100 fold selectivity over VEGFR2(IC50=12 nM) and c-Kit/PDGFR_beta_(IC50=451/217 nM), respectively.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [623142-96-1]
• MW: 480.5362
• Formula: C₂₄H₂₄N₄O₅S
• SMILES: S1C([H])=C([H])N=C1C([H])(C([H])([H])[H])N([H])C(N([H])C1C([H])=C([H])C(=C([H])C=1OC([H])([H])[H])OC1C([H])=C([H])N=C2C([H])=C(C(=C([H])C=12)OC([H])([H])[H])OC([H])([H])[H])=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of Ki20227