KLRG1 (C) Antibody, Rabbit Polyclonal

SKU: orb67025

Description

Rabbit polyclonal to KLRG1.Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a single-pass type II cell membraneprotein that is expressed specifically on natural killer (NK) cells and activated CD8 T-cells and isinduced by pathogens and viral infections. KLRG1 forms monomer and disulfide-linked homodimer.KLRG1 plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to theirnon-MHC ligands. KLRG1 may mediate missing self recognition by binding to a highly conserved siteon classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 andR-cadherin/CDH4 on target cells.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Immunology,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of mouse KLRG1
• Molecular Weight: 21
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-KLRG1 antibody,anti-Killer cell lectinlike receptor subfamily G member 1 antibody,anti-Mast cell functionassociated antigen 2F1 antibody,anti-Mafa antibody

Quick Database Links

UniProt

O88713