LAG3

SKU: orb1945242

Description

Lymphocyte activation gene 3 (LAG3) inhibits antigen activated T-cells upon binding to ligands. Following TCR engagement, LAG3 associates with CD3-TCR in the immunological synapse and directly inhibits T-cell activation. IHC testing of LAG3 can be used as Prognostic marker in renal cancer (unfavorable) and cervical cancer (favorable).

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Monoclonal
• Clone No.: IHC127
• Conjugation: Unconjugated

Storage & Handling

• Storage: Store at 2-8°C. To ensure stability, immediately replace vial back in the refrigerator after each use
• Buffer/Preservatives: Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and < 0.1% Sodium Azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only