LEF1 Antibody / Lymphoid enhancer-binding factor 1 / TCF1 alpha

SKU: orb1823439

Description

Lymphoid Enhancing Factor 1 (LEF1), also called TCF1 alpha, is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.

Images & Validation

• Tested Applications: IHC-P
• Dilution Range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1, kappa
• Clone No.: LEF1/6764
• Immunogen: A recombinant fragment of human LEF1 protein was used as the immunogen for the TCF1 alpha antibody.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Aliquot the TCF1 alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Hazard Information: This TCF1 alpha antibody is available for research use only.
• Disclaimer: For research use only

Quick Database Links

UniProt

Q9UJU2