LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 116-461, His)

SKU: orb1959819

Description

LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 116-461, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.15 kDa and the accession number is Q8NHL6-1.

Research Area

,Recombinant-Protein

Images & Validation

• Application Notes:
  Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Key Properties

• Expression System: HEK293 Cells
• Biological Origin: Human
• Biological Activity: LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 116-461, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.15 kDa and the accession number is Q8NHL6-1.
• Tag: C-His
• Expression Region: Leu116-Val461
• MW: 38.15 kDa (predicted). Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result.
• Purity: 98.00%

Storage & Handling

• Storage: -20°C
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

UniProt

Q8NHL6