LMTK3 inibitor C28

SKU: orb2279792

Description

LMTK3-IN-1 (compound C28) is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM)，that acts by degrading LMTK3 via the ubiquitin-proteasome pathway. LMTK3-IN-1 shows anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 induces apoptosis in BC cell lines at 10-20 μM.

Key Properties

• CAS Number: [2764850-23-7]
• MW: 356.308
• Formula: C₁₈H₁₁F₃N₄O
• SMILES: O(C1=CC=CC(C2=CN=C3C=CC(C4=CC=NC=C4)=NN23)=C1)C(F)(F)F

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only