LP23

SKU: orb2277751

Description

LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration of immune cell function in HepG2/Jurkat T cells and induction of HepG2 cell death. Additionally, LP23 demonstrates in vivo efficacy in the B16-F10 tumor model (TGI=88.6% at 30 mg/kg) [1].

Research Area

,Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation

Key Properties

• MW: 505.59
• Purity: 98.00%
• Formula: C₂₇H₂₇N₃O₅S

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only