Luminespib (NVP-AUY922)

SKU: orb154741

Description

AUY922 (NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 1/2.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

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Item 1 of 1

Key Properties

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CAS Number	[747412-49-3]
MW	465.541
Formula	C₂₆H₃₁N₃O₅
SMILES	O=C(C1=NOC(C2=CC(C(C)C)=C(O)C=C2O)=C1C3=CC=C(CN4CCOCC4)C=C3)NCC

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Chemical structure of Luminespib (NVP-AUY922)

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