MGAT2 Protein, Human, Recombinant (His)

SKU: orb1961231

Description

Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

Research Area

,Recombinant-Protein

Images & Validation

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Key Properties

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Expression System	HEK293 Cells
Biological Origin	Human
Biological Activity	Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
Tag	C-6xHis
Expression Region	Arg30-Gln447
MW	50 KDa (reducing condition)
Purity	98.00%
Protein Sequence	Arg30-Gln447

Storage & Handling

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Storage	-20°C
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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UniProt

Q10469

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