MGMT Antibody

SKU: orb134972

Description

Rabbit polyclonal to MGMT. Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Product Categories/Products/Antibodies/Primary Antibodies,Cancer/DNA Damage,Epigenetics,Crown Antibodies;Primary Antibodies

Images & Validation

• Tested Applications: IF, IHC-P, WB
• Dilution Range: WB: 1:1000
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: 888CT22.2.4
• Immunogen: Recombinant Protein
• Target: MGMT
• Molecular Weight: 21646
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti MGMT antibody, anti Methylated-DNA--protein-cysteine methyltransferase antibody, anti Methylated-DNA--protein-cysteine methyltransferase antibody, anti 6-O-methylguanine-DNA methyltransferase antibody, anti Methylated-DNA--protein-cysteine methyltransferase antibody, anti O-6-methylguanine-DNA-alkyltransferase antibody

Quick Database Links

Gene Symbol

MGMT

UniProt

P16455