MK-4827 (tosylate)

SKU: orb363967

Description

MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; > 330-fold selective against PARP3, V-PARP and Tank1.

Research Area

Product Categories/Products/Small Molecules

Key Properties

• CAS Number: [1038915-73-9]
• MW: 492.5899
• Formula: C₂₆H₂₈N₄O₄S
• SMILES: O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)N.O=S(C5=CC=C(C)C=C5)(O)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only