MKRN1 (N) Antibody, Rabbit Polyclonal

SKU: orb67218

Description

Rabbit polyclonal to MKRN1.E3 ubiquitin-protein ligase makorin-1 (MKRN1) catalyzes the covalent attachment of ubiquitin moietiesonto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. MKRN1supports cell survival by suppressing p53/TP53 under normal conditions, but stimulates apoptosis byrepressing CDKN1A under stress conditions. MKRN1 acts as a negative regulator of telomerase andhas negative and positive effects on RNA polymerase II-dependent transcription.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution Range	WB:1:500-1:2000
Reactivity	Human, Mouse

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human MKRN1
Molecular Weight	53
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Buffer/Preservatives	0.01% NaN3
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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anti-MKRN1 antibody,anti-E3 ubiquitinprotein ligase makorin1 antibody,anti-RING finger protein 61 antibody,anti-RNF61 antibody

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Quick Database Links

UniProt

Q9UHC7

UniProt Details

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No UniProt data available

Protocol Information

Western Blot (IB, immunoblot)

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100 μl

$ 440.00

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