Murine TECK protein

SKU: orb107807

Description

Thymus Expressed Chemokine (TECK)/CCL25 is a novel CC chemokine that is distantly related (approximately 20% aminoacid sequence identity) to other CC chemokines. Mouse CCL25 cDNA has also been cloned and shown to encode a 144 aaprotein that exhibits 49% aa sequence identity to human CCL25. The expresssion of human and mouse CCL25 was shown to behighly restricted to the thymus and small intestine. Although dendritic cells have been demonstrated to be the source of CCL25production in the thymus, dendritic cells derived from bone marrow do not express CCL25. Recombinant human and mouseCCL25 have been shown to be chemotactic for activated macrophages, dendritic cells and thymocytes. CCL25 signals throughthe CCR9 receptor.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: TECK
• Conjugation: Unconjugated
• MW: 14.1 kDa
• Purity: > 95% by SDS-PAGE and HPLC analyses.
• Protein Sequence: QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVCGNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNSTSVRSATLGHP RMVMMPRKTN N

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Murine Thymus Expressed Chemokine /CCL25 protein

SDS-PAGE analysis of Murine TECK protein

Quick Database Links

Gene Symbol

TECK