nor-NOHA HCl

SKU: orb1089662

Description

nor-NOHA, also known as N-?Hydroxy-?nor-?L-?Arginine, is an Arginase inhibitor. nor-NOHA induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. Nor-NOHA can induce cell apoptosis and inhibit the ability of invasion and migration of HepG2 cells by inhibiting Arg1, which is related with the increase of iNOS expression and the high concentration of NO.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Key Properties

• CAS Number: [291758-32-2]
• MW: 176.173780441284
• Formula: C₅H₁₂N₄O₃
• SMILES: O=C(O)[C@@H](N)CCN/C(N)=N/O.[H]Cl.[H]Cl

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only