NVP-BEZ235 Tosylate

SKU: orb341702

Description

BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.

Research Area

Product Categories/Products/Small Molecules

Key Properties

• CAS Number: [1028385-32-1]
• MW: 641.73814
• Formula: C₃₀H₂₃N₅O.C₇H₈O₃S
• SMILES: CN(C1=C2C3=CC(C4=CC5=CC=CC=C5N=C4)=CC=C3N=C1)C(N2C6=CC=C(C=C6)C(C)(C#N)C)=O.CC7=CC=C(S(=O)(O)=O)C=C7

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Chemical structure of NVP-BEZ235 Tosylate