PARP-1-IN-2

SKU: orb2279934

Description

PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis.

Key Properties

• CAS Number: [684234-55-7]
• MW: 424.2794
• Formula: C₂₂H₁₅CL₂N₃O₂
• SMILES: ClC1C([H])=C([H])C(=C([H])C=1[H])C1C2=C([H])C([H])=C([H])C([H])=C2C(N(C([H])([H])C(N([H])C2C([H])=C([H])C([H])=C(C=2[H])Cl)=O)N=1)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only