PARP (M) Antibody, Rabbit Polyclonal

SKU: orb66938

Description

Rabbit polyclonal to PARP.Poly [ADP-ribose] polymerase 1 (PARP) is involved in the base excision repair (BER) pathway bycatalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatinarchitecture and in DNA metabolism. This modification follows DNA damages and appears as anobligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARPpositively regulates the transcription of MTUS1 and negatively regulates the transcription ofMTUS2/TIP150.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Immunology,Product Categories/Products/Antibodies/Primary Antibodies

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: middle region of human PARP
• Molecular Weight: 113
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-PARP antibody,anti-ADPRT antibody,anti-PPOL antibody,anti-Poly [ADPribose] polymerase 1 antibody,anti-PARP1 antibody,anti-NAD(+) ADPribosyltransferase 1 antibody,anti-ADPRT 1 antibody,anti-Poly[ADPribose] synthase 1 antibody

Quick Database Links

UniProt

Q3U1F9