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PARP (N) Antibody, Rabbit Polyclonal

SKU: orb66937

Description

Rabbit polyclonal to PARP.Poly [ADP-ribose] polymerase 1 (PARP) is involved in the base excision repair (BER) pathway bycatalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatinarchitecture and in DNA metabolism. This modification follows DNA damages and appears as anobligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARPpositively regulates the transcription of MTUS1 and negatively regulates the transcription ofMTUS2/TIP150.

Research Area

Product Categories/Products/Antibodies,Epigenetics,Product Categories/Products/Antibodies/Primary Antibodies,Cancer,Cancer/DNA Damage

Images & Validation

Tested ApplicationsWB
Dilution RangeWB:1:1000-1:5000
ReactivityHuman

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenN-terminal region of human PARP
Molecular Weight113
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

Storage-20°C
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-PARP antibody,anti-ADPRT antibody,anti-PPOL antibody,anti-Poly [ADPribose] polymerase 1 antibody,anti-PARP1 antibody,anti-NAD(+) ADPribosyltransferase 1 antibody,anti-ADPRT 1 antibody,anti-Poly[ADPribose] synthase 1 antibody

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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol

Available Sizes

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100 μl
$ 440.00
Choose Conjugation or Carrier Free Version
Free Secondary Antibody (20 ul)0/0

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