PARP1-IN-15

SKU: orb2277968

Description

PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis. It exhibits anti-cancer activity in triple-negative breast cancer (TNBC) cells and patient-derived organoids, making it useful for TNBC research, including cases with or without BRCA1 mutations [1].

Research Area

,DNA Damage/DNA Repair|||Chromatin/Epigenetic

Key Properties

• MW: 264.28
• Purity: 98.00%
• Formula: C₁₆H₁₂N₂O₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only