PF-07957472

SKU: orb2665015

Description

PF-07957472 (Compound 4) is an orally effective inhibitor of the SARS-CoV-2 papain-like protease (PLpro). In NHBE cells infected with SARS-CoV-2, it demonstrated cytopathic effects with an EC50 of 13.9 nM. Additionally, PF-07957472 exhibited antiviral activity in a mouse-adapted COVID-19 infection model.

Research Area

,Microbiology/Virology

Key Properties

• CAS Number: 3041047-51-9
• MW: 480.60
• Purity: 98.00%
• Formula: C₂₉H₃₂N₆O
• SMILES: O=C(NC1(C=2C=C(N=C3C=CC=CC32)C=4C=NN(C4)C)CC1)C5=CC(=CC=C5C)N6CCN(C)CC6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171037455