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PF-4 protein

SKU: orb107795

Description

Recombinant Human Platelet Factor-4/CXCL4. Platelet Factor-4 (PF-4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The gene for human CXCL4 is located on human chromosome 4. This chemokine is released from alpha-granules of activated platelets during platelet aggregation and neutralizes the anticoagulant effect of heparin. It interacts with a splice variant of the chemokine receptor CXCR3 besides be chemotactic for neutrophils, fibroblasts and monocytes. Recombinant human CXCL4 contains 70 amino acids binds with high affinity to heparin. Specifically, Human and mouse CXCL4 share about a 60 % identity.

Images & Validation

Tested ApplicationsHPLC, SDS-PAGE

Key Properties

Biological OriginE.coli
TargetPF-4
ConjugationUnconjugated

Storage & Handling

StorageStore at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide
SDS-PAGE
Sodium Dodecyl Sulphate PolyAcrylamide Gel Electrophoresis
View Protocol
HPLC
High-Performance Liquid Chromatography
View Protocol

PF-4 protein (orb107795)

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Available Sizes

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5 μg
$ 170.00
100 μg
$ 960.00
500 μg
$ 1,910.00
DispatchUsually dispatched within 2-3 weeks
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