Phospho-APP(S730) Antibody

SKU: orb34406

Description

Rabbit polyclonal antibody to APP (phospho-Ser730). The protein belongs to the APP family, and is highly expressed in brain, kidney, heart and spleen. APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. This gene can be phosphorylated at several sites, which may affect the proteolytic processing and secretion of this protein.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Neuroscience,Signaling Pathways,Product Categories/Products/Antibodies/Primary Antibodies,Signaling Pathways/Apoptotic,Signaling Pathways/Alzheimer's,Epigenetics,Primary Antibodies;Antibody Collections;Neuroscience;Phospho Antibodies;Inflammasome

Images & Validation

• Tested Applications: WB
• Dilution Range: WB: 1:1000
• Reactivity: Human
• Predicted Reactivity: Mouse, Porcine, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB6972
• Immunogen: Synthetic Peptide
• Target: APP
• Molecular Weight: 86943
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Amyloid beta A4 protein [Precursor] antibody, anti-APP antibody, anti-ABPP antibody, anti-Alzheimer disease amyloid protein antibody, anti-Cerebral vascular amyloid peptide antibody, anti-CVAP antibody, anti-Protease nexin-II antibody, anti-PN-II antibody, anti-APPI antibody, anti-PreA4 antibody, anti-APP antibody, anti-A4 antibody, anti-AD1 antibody

Quick Database Links

Gene Symbol

APP

UniProt

P05067

RefSeq (Protein):NP_001129602.1, NP_001191232.1, NP_958816.1, NP_001191230.1, NP_000475.1, NP_001129488.1, NP_001129601.1, NP_001191231.1, NP_958817.1, NP_001129603.1