Phospho-DNA PKcs (Ser2056) Rabbit Polyclonal Antibody

SKU: orb5978

Description

Phospho-DNA PKcs (Ser2056) Rabbit Polyclonal Antibody

Research Area

DNA / RNA, Epigenetics and Nuclear Signaling, DNA Repair, DNA and RNA

Images & Validation

• Tested Applications: IF, IHC-Fr, IHC-P
• Dilution Range: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Reactivity: Mouse
• Predicted Reactivity: Equine, Human, Rabbit, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthesised phosphopeptide derived from human DNA PKcs around the phosphorylation site of Ser2056 YS(p-S)QD
• Target: PRKDC
• Molecular Weight: 454 kDa
• Purification: affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNA PK(phospho S2056); p-DNA PK(phospho S2056); PRKDC(phospho T2056); PRKDC_HUMAN; DNA-dependent protein kinase catalytic subunit; EC:2.7.11.1; PRKDC; HYRC; HYRC1; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; p460;

Quick Database Links

Gene Symbol

PRKDC

UniProt

P78527

Inturi, Swetha et al. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes Mutat Res, 763-764, 53-63 (2014)

PubMed: 24732344