Phospho-ERK5 (Ser496) Rabbit Polyclonal Antibody

SKU: orb5183

Description

Phospho-ERK5 (Ser496) Rabbit Polyclonal Antibody

Research Area

Kinases, Kinases, Cell Biology, MAPK/ERK Signalling Pathway, Signal Transduction

Images & Validation

• Tested Applications: ICC, IF, IHC-Fr, IHC-P, WB
• Dilution Range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100, IF=1:100-500
• Reactivity: Human
• Predicted Reactivity: Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated Synthesised phosphopeptide derived from human ERK5 around the phosphorylation site of Ser496 GP(p-S)AP
• Target: MAPK7
• Molecular Weight: 90 kDa
• Purification: affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ERK5(phospho S496); Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; EC 2.7.11.24; ERK 4; ERK 5; ERK-5; ERK4; Extracellular Signal Regulated Kinase 5; Extracellular signal-regulated kinase 5; MAP kinase 7; MAPK 7; MAPK7; Mitogen Activated Protein Kinase 7; Mitogen-activated protein kinase 7; MK07_HUMAN; OTTHUMP00000065906; OTTHUMP00000065907; PRKM 7; PRKM7; PROTEIN KINASE, MITOGEN-ACTIVATED, 7.

Quick Database Links

Gene Symbol

MAPK7

UniProt

Q13164

Arianna Filippelli 1, Valerio Ciccone 1, Cinzia Del Gaudio 1, Vittoria Simonis 1, Maria Frosini 1, Ignazia Tusa 2, Alessio Menconi 2, Elisabetta Rovida 3, Sandra Donnini ERK5 mediates pro-tumorigenic phenotype in non-small lung cancer cells induced by PGE2 Biochim Biophys Acta Mol Cell Res, (2024)

PubMed: 39128596

Applications

WB

Reactivity

Human