Phospho-Nrf2 (Ser40) Rabbit Polyclonal Antibody

SKU: orb6544

Description

Phospho-Nrf2 (Ser40) Rabbit Polyclonal Antibody

Research Area

CARdiovascular Research, Mitochondrial Biogenesis, Cell Biology, Oxidative Stress, mitochondrial transcription, DNA and RNA

Images & Validation

• Tested Applications: ICC, WB
• Dilution Range: WB=1:500-2000, ICC/IF=1:100
• Reactivity: Human, Mouse
• Predicted Reactivity: Bovine, Canine, Gallus, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40 DF(p-S)QR
• Target: NFE2L2
• Molecular Weight: 68 kDa
• Purification: affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Nrf2(phospho S40); p-Nrf2(phospho S40); Nuclear factor-E2 related factor2; HEBP1; NF E2 related factor 2; NFE2 related factor 2; NFE2L2; Nrf 2; Nuclear factor erythroid 2 related factor 2; Nuclear factor erythroid derived 2 like 2; NF2L2_HUMAN.

Quick Database Links

Gene Symbol

NFE2L2

UniProt

Q16236

Helia Aghamiri # 1 2, Afrooz Mohammadgholi-Beiki # 3, Rojin Rashidian 1 3, Manijeh Motevalian 1 3, Parvaneh Rahimi-Moghaddam 3, Mohammad Sheibani # 4 5, Majid Jafari-Sabet Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways Inflammopharmacology, (2024)

PubMed: 39312096

Applications

WB

Reactivity

Rat

Afrooz Mohammadgholi-Beiki 1, Helia Aghamiri 2, Rojin Rashidian 1, Majid Jafari-Sabet 1 3, Manijeh Motevalian 1 3, Parvaneh Rahimi-Moghaddam 4, Mohammad Sheibani Investigation of the Protective Effects of Aripiprazole on Methylphenidate-induced Neurotoxicity in Rats Mol Neurobiol, (2025)

PubMed: 40299297

Applications

WB

Reactivity

Rat

Gupta, Mahesh et al. Dwindling of cardio damaging effect of isoproterenol by Punica granatum L. peel extract involve activation of nitric oxide-mediated Nrf2/ARE signaling pathway and apoptosis inhibition Nitric Oxide, 50, 105-113 (2015)

PubMed: 26363155

Applications

IHC

Reactivity

Rat