Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Ponatinib (AP24534)

SKU: orb154625

Description

AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

Key Properties

CAS Number[943319-70-8]
MW532.56
FormulaC29H27F3N6O
SMILESCC1=C(C=C(C=C1)C(NC2=CC(C(F)(F)F)=C(C=C2)CN3CCN(CC3)C)=O)C#CC4=CN=C5N4N=CC=C5

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • AP24534 hydrochloride [orb2703372]

    [1114544-31-8]

    569.02

    C29H28CLF3N6O

    100 mg, 250 mg, 1 g
  • Ponatinib (AP24534) [orb1101932]

    > 98%

    [943319-70-8]

    532.56

    C29H27F3N6O

    20 mg
  • AP24534 (Ponatinib) [orb1905510]

    943319-70-8

    1 ml x 10 mm (in DMSO)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Ponatinib (AP24534)

Chemical structure of Ponatinib (AP24534)

Documents Download

Datasheet
Product Information
Download
MSDS
Safety Data Sheet
Download

Request a Document

Protocol Information

Ponatinib (AP24534) (orb154625)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 ml x 10 mm (in DMSO)
$ 300.00
100 mg
$ 360.00
250 mg
$ 620.00
1 g
$ 1,150.00
DispatchUsually dispatched within 5-10 working days.
Bulk Enquiry