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PRMT5-IN-45

SKU: orb2695571

Description

PRMT5-IN-45 (compound 36) is a potent and selective inhibitor of PRMT5, exhibiting an IC50 value of 3 nM. This compound effectively reduces the levels of symmetrical dimethylarginine (sDMA) and inhibits the proliferation of the MOLM-13 cell line by inducing apoptosis and causing cell cycle arrest.

Research Area

,Apoptosis|||Chromatin/Epigenetic

Images & Validation

Key Properties

MW473.57
FormulaC26H31N7O2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information