Prostein Antibody / SLC45A3

SKU: orb1824242

Description

Human prostein is a 553 aa protein identified by cDNA library subtraction and subsequent high-throughput microarray screening of prostate cancer. Prostein has multiple transmembrane domains. Prostein has been shown to be uniquely expressed in normal and cancerous prostatic tissues. By immunohistochemistry, prostein is expressed in the vast majority of normal and malignant prostatic tissues, regardless of grade and metastatic status. No protein expression is detected in normal and malignant tissue samples representing the great majority of essential tissues and tumors. In particular, prostein is expressed in most of poorly differentiated prostatic carcinoma, including small cell prostate carcinoma. Prostein is more specific and sensitive for prostatic carcinomas than PSA and PSAP.

Images & Validation

• Tested Applications: IHC-P
• Dilution Range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1, kappa
• Clone No.: SLC45A3/7649
• Immunogen: A recombinant partial protein sequence (within amino acids 300-500) from the human protein was used as the immunogen for the Solute carrier family 45 member 3 antibody.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Aliquot the Solute carrier family 45 member 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Hazard Information: This Solute carrier family 45 member 3 antibody is available for research use only.
• Disclaimer: For research use only

IHC staining of FFPE human prostate tissue with Solute carrier family 45 member 3 antibody (clone SLC45A3/7649). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

IHC staining of FFPE human prostate tissue with Solute carrier family 45 member 3 antibody (clone SLC45A3/7649). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

Quick Database Links

UniProt

Q96JT2