Quizartinib (AC220)

SKU: orb154726

Description

Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 1/2.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

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Key Properties

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CAS Number	[950769-58-1]
MW	560.673
Formula	C₂₉H₃₂N₆O₄S
SMILES	N(C1C=C(C(C)(C)C)ON=1)C(NC1=CC=C(C2=CN3C4=CC=C(OCCN5CCOCC5)C=C4SC3=N2)C=C1)=O

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Chemical structure of Quizartinib (AC220)

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