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(R)-JAK2/STAT3-IN-10a

SKU: orb2283868

Description

(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.

Research Area

,Immunology/Inflammation

Images & Validation

Key Properties

CAS Number2485758-49-2
MW682.57
Purity98.34%
FormulaC34H35BrF3N5O2
SMILESC(N)(=O)N1[C@@H](C=2C=3C(N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C2)=CC=C(Br)C3)CC(=N1)C6=CC=C(C(F)(F)F)C=C6

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 300.00
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100 mg
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