Randox - Interleukin-12p35 (IL-12p35)

SKU: RCP9265

Description

Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation.

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Protein Length: Arg23- Ser219
• MW: 27.04 kDa
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid
• Buffer/Preservatives: 20 mM Tris-HCl pH 8.0, 1 mM EDTA, 50 % Glycerol
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IL-12A; Cytotoxic Lymphocyte Maturation Factor; CLMF; Natural Killer Cell Stimulation Factor 1; NKSF1; NFSK; subunit p35.

Quick Database Links

UniProt

P29459