Randox - Interleukin-12p40 (IL-12p40)

SKU: RCP9122

Description

Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation.

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Protein Length: Ile23- Ser328
• MW: 39.2 kDa
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid
• Buffer/Preservatives: 25 mM Sodium phosphate pH 7, 50% Glycerol
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IL-12B; subunit p40, cytotoxic lymphocyte maturation factor 2; p40; natural killer cell stimulatory factor 2; CLMF, CLMF2, NKSF, NKSF2.

Quick Database Links

UniProt

P29460