Randox - Interleukin-17 (IL-17) (Western Blot Control)

SKU: RCP9398

Description

Interleukin 17A (IL-17A) is the original member of the IL17 family of structurally related cytokines (IL-17 A to IL17F) that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17A is a pro-inflammatory cytokine produced primarily by T cells and is commonly associated with the allergic response facilitating the release of other cytokines, chemokines and prostaglandins from a variety of cell types. IL-17A exists in vitro as a homodimer of two 132 amino acid chains.

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Protein Length: Gly24-Ala155
• MW: 19.62 kDa
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH 6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).
• Buffer/Preservatives: 1X Laemmli buffer
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IL-17, Cytotoxic T-lymphocyte associated serine esterase 8; CTLA8.

Quick Database Links

UniProt

Q16552