Randox - Pencillin Binding Protein 2X (PBP-2X)

SKU: RCP9492

Description

Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Penicillin Binding Protein 2X is a membrane bound transpeptidase belong to the high molecular weight class B group of penicillin binding proteins. This enzyme is one of the primary targets of betalactam antibiotics in Streptococcus pneumoniae. Betalactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins.

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Molecular Weight: 81.18 kDa
• Protein Length: Thr50-Asp750
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid
• Buffer/Preservatives: 1XPBS, 50% Glycerol
• Disclaimer: For research use only

Alternative Names

PBP-2X; PBP2x; pbpx.

Quick Database Links

UniProt

P59676