Randox - ST-2

SKU: RCP9388

Description

The ST2 gene is a member of the IL-1 receptor family, encoding a transmembrane protein with a structure similar to IL-1R1. A soluble form of the protein (ST2) is produced from the same gene by alternative splicing and is reported to be expressed in several cell types including fibroblasts and mast cells. Soluble ST2 has been reported to act as a negative regulator of Th2 cytokine production and elevated levels have been reported in several disease states and conditions including asthma, sepsis and myocardial infarction

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Protein Length: Lys19-Phe328
• MW: 39.5 kDa
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid
• Buffer/Preservatives: 25mM Sodium Acetate pH 4.8, 50% Glycerol
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Interleukin-1 Receptor-like 1; IL1R1; Homolog of mouse growth stimulation expressed gene; Homolog of mouse ST2

Quick Database Links

UniProt

Q01638