Randox - Tissue Inhibitor of Metalloproteinase 1 (TIMP-1)

SKU: RCP9172

Description

TIMP-1 is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the Nterminal domain binding to the MMP substrate-binding site. TIMP-1 also functions as erthyroid-potentiating activity via translocation to the nucleus and also in inhibiting apoptosis in B-cells.

Research Area

,For R&D Purposes

Images & Validation

• Application Notes:
  ELISA, Western Blotting, etc.

Key Properties

• Source: E.coli -derived human recombinant protein
• Expression System: E.coli
• Tag: N terminal containing a HIS tag
• Protein Length: Cys24-Ala207
• MW: 25.21 kDa
• Purity: > 95 %, by SDS-PAGE under reducing conditions

Storage & Handling

• Storage: at -20 °C
• Form/Appearance: Liquid
• Buffer/Preservatives: 25mM Sodium Acetate pH 4.8, 50% Glycerol
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Soluble tumour necrosis factor receptor-1; Tumour necrosis factor receptor subfamily member 1A (TNFRSF1A); Tumour necrosis factor binding protein I (TNFBPI); Tumour necrosis factor receptor type I (TNFRI); Tumour necrosis factor-alpha receptor (TNFAR); CD120a antigen; p55; p55-R; p60; MGC19588.

Quick Database Links

UniProt

P01033