RARB Antibody (Center)

SKU: orb106954

Description

Rabbit polyclonal to RARB. Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5-AGGTCA-3 sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Primary Antibodies;Cancer;Signal Transduction

Images & Validation

• Tested Applications: WB
• Dilution Range: WB: 1:1000
• Reactivity: Human
• Predicted Reactivity: Mouse

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB42808
• Immunogen: Synthetic Peptide
• Target: RARB
• Molecular Weight: 50489
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti RARB antibody, anti HAP antibody, anti NR1B2 antibody, anti Retinoic acid receptor beta antibody, anti Retinoic acid receptor beta antibody, anti HBV-activated protein antibody, anti Retinoic acid receptor beta antibody, anti Nuclear receptor subfamily 1 group B member 2 antibody, anti Retinoic acid receptor beta antibody, anti RAR-epsilon antibody

Quick Database Links

Gene Symbol

RARB

UniProt

P10826

RefSeq (Protein):NP_000956.2, NP_057236.1