Rat BD-4 protein

SKU: orb107690

Description

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important armof the innate immune system. The B-defensins are distinguished from the C-defensins by the pairing of their three disulfide bonds.To date, four rat C-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. The C-defensin proteins are expressed as the Cterminalportion of precursors and are released by proteolytic cleavage of a signal sequence. C-defensins contain a six-cysteinemotif that forms three intra-molecular disulfide bonds. C-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acidresidues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: BD-4
• Conjugation: Unconjugated
• MW: 4.4KDa
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Protein Sequence: QSINNPITCL TKGGVCWGPC TGGFRQIGTC GLPRVRCCKK K

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in 10mM PB, pH 7.4, 500mM NaCl.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rat beta-Defensin 4 protein

SDS-PAGE analysis of Rat BD-4 protein

Quick Database Links

Gene Symbol

BD-4