Rat CCL22 protein

SKU: orb107782

Description

Recombinant Rat Macrophage-Derived Chemokine/CCL22. CCL22 is a protein encoded by the CCL22 gene. It is highly expressed in macrophage, monocyte-derived dendritic cell and thymus, additionally, also detected in the tissues of thymus, lymph node and appendix. CCL22 can bind to CCR4, and is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells, but not for neutrophils, eosinophils, and resting T-lymphocytes. After secreted from monocyte-derived dendritic cells, the protein can be proteolytic cleaved into three forms: MDC (3-69), MDC (5-69), MDC (7-69).

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Source: E.coli
• Biological Activity: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-100 ng/ml.
• Target: CCL22/MDC
• Reactivity: Rat
• Endotoxins: Less than 1 EU/μg of rRtMDC/CCL22 as determined by LAL method.
• Conjugation: Unconjugated
• MW: 7.9 kDa
• Purity: > 96% by SDS-PAGE and HPLC analyses
• Protein Sequence: GPYGANVEDS ICCQDYIRHP LPPRFVKEFY WTSKSCRKPG VVLITIKNRD ICADPRMLWVKKILHKLA

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in 2xPBS, pH7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

A 152E5.1 protein, ABCD 1 protein, C C motif chemokine 22 protein, CC chemokine STCP 1 protein, CC chemokine STCP-1 protein, ccl 22 protein, Ccl22 protein, CCL22_HUMAN protein, Chemokine (C C motif) ligand 22 protein, DCBCK protein, Macrophage-derived chemokine protein, MDC protein, Small inducible cytokine subfamily A member 22 protein, Small-inducible cytokine A22 protein, STCP 1 protein, Stimulated T cell chemotactic protein 1 protein

SDS-PAGE analysis of Rat CCL22 protein

Quick Database Links

Gene Symbol

CCL22/MDC