Rat GDNF protein

SKU: orb107728

Description

Glial cell-derived neurotrophic factor, also known as GDNF is a small protein that potently promotes the survival morphologicaldifferentiation of various neuronal which is encoded by the GDNF gene. Furthermore, it may also modulate local neuronal effectsin distal regions of the motor neuron. In addition, GDNF is a founding member of the GDNF family of ligands (GFL) and hasbeen shown to interact with GFRA2 and GDNF family receptor alpha 1. Recombinant rat GDNF (monomer) contains 135 aminoacids residues, which is a disulfide-linked homodimer and it shares 99 % and 93 % a.a. sequence identity with mouse and humanGDNF

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: GDNF
• Conjugation: Unconjugated
• MW: 15.2 kDa
• Purity: > 95 % by SDS-PAGE and HPLC analyses
• Protein Sequence: MSPDKQAAAL PRRERNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLNVTDLGLGYET KEELIFRYCS GSCEAAETMY DKILKNLSRS RRLTSDKVGQACCRPVAFDD DLSFLDDSLV YHILRKHSAK RCGCI

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, 500 mM NaCl, pH 6.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rat Glial Cell-derived Neurotrophic Factor protein

Quick Database Links

Gene Symbol

GDNF