Rat SCF protein

SKU: orb107801

Description

Stem Cell Factor (SCF) which binds to the c-Kit receptor is produced by fibroblasts and endothelial cells. The soluble andtransmembrane forms of the protein are formed by alternative splicing of the same RNA transcript and the presence of bothsoluble and transmembrane SCF is required for normal hematopoietic function. SCF plays an important role in hematopoiesis,spermatogenesis, and melanogenesis. In addition, it also promotes mast cell adhesion, migration, proliferation, and survival 3.Rat SCF shares 75% - 90% a.a. sequence identity with canine, feline, mouse, and human SCF. Furthermore, rat SCF is active onmouse and human cells, but human SCF is only weakly active on mouse cells.

Images & Validation

• Tested Applications: HPLC, SDS-PAGE

Key Properties

• Biological Origin: E.coli
• Target: SCF
• Conjugation: Unconjugated
• MW: 18.5 kDa
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Protein Sequence: MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMVTHLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRNFTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

Storage & Handling

• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rat Stem Cell Factor protein

Quick Database Links

Gene Symbol

SCF