Recombinant Human Heat stable bFGF

SKU: orb1921833

Description

FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively[1]. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization[2].FGF basic/bFGF Protein, Human (145a.a, His), consists of 145 amino acids, produced by E.coli with tag free.

Images & Validation

• Application Notes:
  Application Notes: For research use only. Minimum Sample Size: 1 mg/vial

Key Properties

• Source: E.coli
• Expression System: E.coli
• Biological Origin: Human
• Endotoxins: ≤100 EU/mg
• MW: 16.4kDa
• Purity: ≥95%

Storage & Handling

• Storage: Use a manual defrost freezer and avoid repeated freeze - thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -90°C under sterile conditions after reconstitution.
• Form/Appearance: Lyophilized Powder
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BFGF; FGFB; FGF-2; HBGF-2

Quick Database Links

UniProt

P09038

NCBI Gene ID

2247