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Recombinant Human Interleukin-6 Receptor Subunit Alpha
Description
Images & Validation
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Key Properties
−| Source | Spodoptera frugiperda, Sf21 (baculovirus). |
|---|---|
| Expression System | Spodoptera frugiperda, Sf21 (baculovirus). |
| Biological Activity | Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is 5-15 ng/ml. |
| Endotoxins | Less than 1 EU/ug of rHuIL-6 Rα as determined by LAL method. |
| MW | Apparent molecular mass of 45-50 kDa in SDS-PAGE under reducing conditions, a single glycosylated polypeptide protein consisting of 339 amino acids. |
| Purity | > 97 % by SDS-PAGE analyses. |
| Protein Sequence | Leu20-Asp358; |
Storage & Handling
−| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. -12 months from date of receipt, -20 to -70 °C as supplied. -1 month, 2 to 8 °C under sterile conditions after reconstitution. -3 months, -20 to -70 °C under sterile conditions after reconstitution. |
|---|---|
| Form/Appearance | Lyophilized from 0.2 μm filtered concentrated solution in PBS. |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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