Recombinant Human OSM(his Tag)

SKU: orb1921820

Description

Oncostatin M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is most closely related to leukemia inhibitory factor (LIF) and it in fact utilizes the LIF receptor in addition to its specific receptor in the human. A biologically active OSM receptor has been previously described that consists of a heterodimer of leukemia inhibitory factor receptor (LIFR) and gp130. OSM is synthesized by stimulated T-cells and monocytes. The effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. Recombinant human OSM has approximately 40% and 39% amino acid sequence identity with rat and murine OSM.

Images & Validation

• Application Notes:
  Application Notes: For research use only. Minimum Sample Size: 50μg/vial

Key Properties

• Source: CHO Cell
• Expression System: Eukaryotic cell
• Biological Origin: Human
• Endotoxins: ≤10 EU/mg
• MW: 26.8 kDa
• Purity: ≥95%

Storage & Handling

• Storage: Use a manual defrost freezer and avoid repeated freeze - thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
• Form/Appearance: Lyophilized Powder
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MGC20461; oncostatin M; oncostatin-M

Quick Database Links

UniProt

P13725

NCBI Gene ID

5008