Recombinant NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody

SKU: orb2315756

Description

Recombinant NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody

Research Area

,AKT Signaling|Mesenchymal Stem Cell Differentiation|Neuroscience|Nuclear Marker|Signal Transduction|Stem Cell Differentiation

Images & Validation

• Tested Applications: IHC, WB
• Dilution Range: Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.
• Reactivity: Human
• Application Notes:
  Positive Control: Neuronal axons, Schwann cells and perineural cells of peripheral nerves or tumors of nerve sheath differentiation e. G. Schwannoma, Neurofibroma. Soma and axons of sensory neurons and ganglionic satellite cells. Melanomas.

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: NGFR/2550R
• Immunogen: Recombinant human p75 NGFR protein fragment (around aa 281-421) (exact sequence is proprietary)
• Target: NGFR
• Source/Expression System: HEK293 cells
• Molecular Weight: 75kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR); p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)

Quick Database Links

Gene Symbol

NGFR

UniProt

P08138

NCBI Gene ID

4804