Recombinant Thymidylate Synthase (5-FU Resistance Marker) Antibody

SKU: orb2309438

Description

Recombinant Thymidylate Synthase (5-FU Resistance Marker) Antibody

Research Area

,Cardiovascular

Images & Validation

• Tested Applications: IHC
• Dilution Range: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
• Reactivity: Human
• Application Notes:
  Positive Control: MOLT4; Ramos, 5-FU-resistant colon carcinoma cell lines (NCI H630R10, NCI H630R1); 5-FU-resistant breast cancer cell lines, MCF-Ad5 and MCF-Ad10. Testicular carcinomas.

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: TYMS/9091R
• Immunogen: Recombinant human thymidylate synthase protein fragment (around aa 1-200) (exact sequence is proprietary)
• Target: TYMS
• Source/Expression System: CHO cells
• Molecular Weight: 36kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

dTMP synthase, TMS, TS, TSase, TYMS protein, Tyms thymidylate synthetase

Quick Database Links

Gene Symbol

TYMS

UniProt

P04818

NCBI Gene ID

7298