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SAG

SKU: orb315318

Description

SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ~ 3 nM).

Research Area

Product Categories/Products/Small Molecules

Images & Validation

Key Properties

CAS Number[912545-86-9]
MW490.06
FormulaC28H28ClN3OS
SMILESO=C(C1=C(Cl)C2=CC=CC=C2S1)N([C@H]3CC[C@H](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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SAG

Chemical structure of SAG

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SAG (orb315318)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 ml x 10 mm (in DMSO)
$ 390.00
100 mg
$ 950.00
250 mg
$ 1,800.00
1 g
$ 3,370.00
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