Salermide

SKU: orb16641

Description

Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 μM) by reactivating proapototic genes that are repressed by SIRT1.

Research Area

Product Categories/Products/Small Molecules

Key Properties

• CAS Number: [1105698-15-4]
• MW: 394.47
• Formula: C₂₆H₂₂N₂O₂
• SMILES: OC1=CC=C2C=CC=CC2=C1/C=N/C3=CC(NC(C(C)C4=CC=CC=C4)=O)=CC=C3

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only