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SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)
SKU: orb1960912
Description
Research Area
,Recombinant-Protein
Images & Validation
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Key Properties
−| Expression System | E. coli |
|---|---|
| Biological Origin | SARS-CoV-2 |
| Biological Activity | The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14. |
| Tag | N-6xHis |
| Expression Region | Ala1-Gln527 |
| MW | 60 KDa (reducing condition) |
| Purity | 98.00% |
| Protein Sequence | Ala1-Gln527 |
Storage & Handling
−| Storage | -20°C |
|---|---|
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
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Protocol Information
Protein Handling and Storage Guide
Protein Handling Guide
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