SARS-CoV-2 Mpro-IN-2

SKU: orb1686944

Description

SARS-CoV-2 Mpro-IN-2

Research Area

Product Categories/Products/Small Molecules,Microbiology/Virology

Key Properties

• CAS Number: 2768834-39-3
• MW: 475.39
• Purity: 98%
• Formula: C₂₂H₂₀Cl₂N₄O₂S
• SMILES: C(NCC1=CC=CS1)(=O)[C@H]2N(CCN(C(=O)C=3C=CC=NC3)C2)C4=CC(Cl)=C(Cl)C=C4

Bioactivity

• Target IC50:
  Mpro:0.40 μM|Vero E6:100 μM (CC50)
• In Vivo:
  In male Sprague-Dawley rats, SARS-CoV-2 Mpro-IN-2 (2 mg/kg intravenous injection; 10 mg/kg oral administration; single dose) exhibited favorable pharmacokinetic parameters .
  Read more...
• In Vitro:
  In Vero E6 cells, SARS-CoV-2 Mpro-IN-2 (0.01-100 μM; 4 hours) exhibited low cytotoxicity, with a CC50 value exceeding 100 μM.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164946686